What is CRISPR?
CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) is a revolutionary gene‑editing technology that enables precise, cheap, and efficient modifications to DNA.
Key Milestones
2012 – Jennifer Doudna & Emmanuelle Charpentier demonstrate CRISPR–Cas9 editing in vitro.
2013 – First use of CRISPR to edit mammalian cells.
2015 – First CRISPR therapy in human embryos (controversial).
2017 – First clinical trial using CRISPR for sickle cell disease.
2020 – FDA approves first CRISPR‑based diagnostic test.
2023 – First FDA‑approved CRISPR therapy for hereditary blindness.
Interactive Guide RNA Designer
Adjust the slider to see how changing the guide RNA length affects target specificity.